10 Iconic ‘Grey’s Anatomy’ Episodes You Can’t Miss Before Season 21 Drops

Introduction: Anticipation is Building for Grey’s Anatomy Season 21

As fans eagerly wait for the return of Grey’s Anatomy with its highly anticipated season 21, it’s the perfect time to revisit some unforgettable episodes from the past. The series has given us countless iconic moments, shocking twists, and emotional rollercoasters over the years. Whether you’re a long-time fan or a newcomer to the show, these episodes never fail to bring the drama, the laughs, and the tears.

In this article, we’ve compiled a list of 10 Grey’s Anatomy episodes to rewatch while you count down the days to the new season. These episodes showcase the heart and soul of Grey’s Anatomy—the characters, their journeys, and the unforgettable moments that have defined the series.


Why Revisit ‘Grey’s Anatomy’ Episodes Before Season 21?

Before diving into the best episodes, let’s talk about why revisiting these episodes is essential while we wait for season 21. First, it’s a great way to refresh your memory on key storylines and character arcs. Second, there are certain episodes that never get old—they continue to make us laugh, cry, and reflect on the power of love, loss, and healing.

As we prepare for new storylines and character developments in season 21, it’s only fitting that we take a trip down memory lane. By revisiting these top episodes, you’ll reignite your love for the show and get ready for what’s to come.


1. “It’s the End of the World” (Season 2, Episode 16)

Why It’s a Must-Watch: In this high-stakes episode, a bomb is discovered inside a patient’s chest, leading to a tense, heart-pounding situation at Seattle Grace Hospital. This is one of the most intense episodes in Grey’s Anatomy history, combining suspense with emotional depth as the characters face their fears and confront what really matters.

Key Moments:

  • Meredith’s emotional vulnerability.
  • The bomb squad standoff.
  • The powerful relationship development between Meredith and Derek.

This episode lays the foundation for the Meredith and Derek relationship, making it a pivotal moment in the series.


2. “The First Cut is the Deepest” (Season 4, Episode 1)

Why It’s a Must-Watch: The Season 4 premiere introduces a new chapter for the characters of Seattle Grace. With the arrival of new interns and new challenges, it’s a whirlwind of emotions from the get-go. This episode also features the return of Dr. Burke, which leaves fans both excited and conflicted.

Key Moments:

  • The tension between Meredith and Derek.
  • New intern dynamics.
  • Burke’s return and his relationship with Cristina.

This episode offers fresh starts, new beginnings, and a glimpse into the future of the hospital and its residents.


3. “Chasing Cars” (Season 2, Episode 27)

Why It’s a Must-Watch: This season finale brings so much drama and heartbreak. As the title suggests, “Chasing Cars” is one of the most emotionally charged episodes, filled with unexpected twists. The song “Chasing Cars” by Snow Patrol, which plays during the episode, became synonymous with Grey’s Anatomy and continues to evoke a sense of longing and nostalgia.

Key Moments:

  • The aftermath of the ferry boat crash.
  • The fate of George and Izzie’s friendship.
  • Meredith’s internal struggle with her feelings for Derek.

This episode perfectly captures the emotional complexity of the characters while delivering an unforgettable cliffhanger.

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4. “Drowning on Dry Land” (Season 2, Episode 25)

Why It’s a Must-Watch: This is a heart-wrenching episode that highlights the medical drama at its finest. The staff is forced to confront their own vulnerabilities when a severe trauma case comes through the doors. The emotional and professional dynamics are at their peak here.

Key Moments:

  • Dr. Bailey’s struggles with her new role as a mother.
  • The emotional weight of the trauma case.
  • Meredith’s fractured relationship with her father.

This episode marks a turning point in many relationships and explores the complexity of life and death.


5. “Sanctuary” (Season 5, Episode 23)

Why It’s a Must-Watch: This is the first part of a two-episode finale that’s packed with drama. A shooter enters Seattle Grace Hospital, resulting in chaos and a tense standoff. It’s a perfect example of how Grey’s Anatomy can take the viewers from gripping tension to emotional catharsis in the blink of an eye.

Key Moments:

  • The arrival of the shooter.
  • The emotional journey of the characters trying to survive.
  • Key moments between Meredith and Derek.

The stakes are higher than ever, making this one of the most intense episodes in the show’s history.


6. “Love/Addiction” (Season 4, Episode 17)

Why It’s a Must-Watch: “Love/Addiction” is a fascinating exploration of the complicated relationships between the doctors. The characters’ personal and professional lives collide in unexpected ways, bringing out new dimensions of their personalities.

Key Moments:

  • The continuation of the Meredith-Derek saga.
  • Alex and Izzie’s developing relationship.
  • Cristina and Burke’s complicated romance.

This episode deals with the conflicting nature of love and addiction, adding depth to the character arcs.


7. “The Time Warp” (Season 7, Episode 17)

Why It’s a Must-Watch: This one’s a fan favorite because of its lighthearted, yet deeply emotional, moments. The episode uses a unique time loop concept, allowing the characters to reflect on their pasts while navigating the present. It’s a delightful mix of humor and vulnerability.

Key Moments:

  • The quirky time loop plotline.
  • Reflective moments for key characters like Meredith and Cristina.
  • Emotional growth and realization.

It’s a perfect episode to revisit when you need something a bit more lighthearted but still deeply impactful.


8. “As We Know It” (Season 2, Episode 17)

Why It’s a Must-Watch: In this gripping episode, the hospital faces a crisis after a bomb is discovered in a patient’s chest. With lives at risk, the staff must band together and face their worst fears.

Key Moments:

  • The intense moments of suspense.
  • The relationships between the characters as they face death.
  • Meredith’s self-discovery.

This episode is one of the most dramatic in Grey’s Anatomy history and is a must-watch for any fan.


9. “Death and All His Friends” (Season 6, Episode 24)

Why It’s a Must-Watch: The Season 6 finale is a game-changer, leaving fans at the edge of their seats. A violent shooting spree at Seattle Grace Hospital shakes everyone to their core, forcing the doctors to make life-changing decisions.

Key Moments:

  • The aftermath of the shooting.
  • Heartbreaking decisions that will impact the hospital’s future.
  • Intense character moments between Meredith and Derek.

It’s a sobering, emotional finale that’s not to be missed.


10. “All I Want Is You” (Season 6, Episode 23)

Why It’s a Must-Watch: The episode builds on the suspense of the previous one, leading into the shocking season finale. We see emotional confrontations, pivotal character moments, and a heightened sense of urgency.

Key Moments:

  • The developing crisis at the hospital.
  • Meredith and Derek’s heartfelt moments.
  • The emotional toll the events take on the characters.

It’s a powerful episode that sets up the heartbreaking finale to perfection.


Conclusion: Get Ready for More Drama with ‘Grey’s Anatomy’ Season 21

Revisiting these Grey’s Anatomy episodes is the perfect way to get your fix while you wait for the long-anticipated return of Season 21. From intense moments of suspense to deep emotional journeys, these episodes remind us why Grey’s Anatomy remains one of the most beloved shows on television. Whether you’re looking for drama, love, or heartache, these episodes have it all.

As we gear up for the new season, these episodes provide the perfect way to refresh your memory, get excited about what’s to come, and appreciate the show’s lasting impact on fans.


Frequently Asked Questions (FAQs)

1. What is the best season of Grey’s Anatomy to watch? It depends on what you’re looking for! For drama and intense moments, Season 2 and Season 6 are great. If you prefer character development, Season 4 offers some of the best moments.

2. What is the most emotional episode of Grey’s Anatomy? Many fans agree that “Chasing Cars” from Season 2 is one of the most emotional, due to its poignant moments and the emotional journey of the characters.

3. Will there be a Season 21 of Grey’s Anatomy? Yes! Season 21 is currently in production and will be releasing soon, much to the excitement of fans everywhere.

4. Where can I watch Grey’s Anatomy Season 21? Season 21 will likely be available on ABC and streaming platforms like Hulu or Disney+ after its television broadcast.

5. Is Grey’s Anatomy still worth watching? Absolutely! With its deep character development, emotional moments, and ever-evolving storylines, Grey’s Anatomy continues to captivate viewers and remains a must-watch show.

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